Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular genetics of meningiomas: Building the roadmap towards personalized therapy.

Neuro-Chirurgie - 1 Mar 2018

Peyre M, Kalamarides M

Abstract excerpt

New advances have recently been made in the field of molecular genetics and mouse modeling of meningiomas, opening new perspectives for future treatments. Recent genome-wide genotyping and exome sequencing studies have confirmed the pivotal role of NF2 in meningioma tumorigenesis, concerning roughly half of the tumors, and unraveled new mutations in non-NF2 meningiomas concerning AKT1, SMO, KLF4 and TRAF7. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to SMO gene
Share to Genes, Neurofibromatosis 2
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kruppel-Like Factor 4

Share to Meningeal Neoplasms

Share to Meningioma

Share to Mutation

Share to Precision Medicine

Source

Identifiers

PMID: 25245924
DOI: 10.1016/j.neuchi.2014.06.007

Genes

NF2
AKT1
KLF4
SMO
TERT
TRAF7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular genetics of meningiomas: Building the roadmap towards personalized therapy.PMID 25245924Read ↗

Meningioma: current updates on genetics, classification, and mouse modeling.Semantic proximity Read ↗

Molecular alterations in meningioma: prognostic and therapeutic perspectivesSemantic proximity Read ↗

A new amplicon-based gene panel for next generation sequencing characterization of meningiomas.Semantic proximity Read ↗

High-grade meningiomas: biology and implications.Semantic proximity Read ↗

Meningioma Genomics: Diagnostic, Prognostic, and Therapeutic ApplicationsSemantic proximity Read ↗

Clinical potential of meningioma genomic insights: a practical review for neurosurgeons.Semantic proximity Read ↗

Genetic landscape of meningioma.Semantic proximity Read ↗

Meningioma genomics: a therapeutic challenge for cliniciansSemantic proximity Read ↗

[Clinicopathological and molecular features of meningioma: an analysis of 134 cases based on high-throughput sequencing].Semantic proximity Read ↗

Genomic Biomarkers of Meningioma: A Focused ReviewSemantic proximity Read ↗

MOLECULAR GENETICS OF MENINGIOMASSemantic proximity Read ↗

Molecular genetics of meningiomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.