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Circular RNA Profile of Breast Cancer Brain Metastasis: Identification of Potential Biomarkers and Therapeutic Targets

1 Dec 2018

Abstract excerpt

AIM: To explore the circular RNA (circRNA) profile of breast cancer brain metastasis (BCBM). MATERIALS & METHODS: RNA-seq was performed to identify the circRNA expression profile of brain metastatic breast cancer cell line 231-BR, in comparison with its parental nonspecific metastatic cell line MDA-MB-231. RESULTS: A total of 215 upregulated and 191 downregulated circRNAs were identified. The expression levels of...

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PMID: 30810051
DOI: 10.2217/epi-2018-0090

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