Article
BRCA and PALB2 mutations in a cohort of male breast cancer with one bilateral case.
European journal of medical genetics - 1 Jun 2020
Vietri Maria Teresa, Caliendo Gemma, D'Elia Giovanna, Resse Marianna, Casamassimi Amelia, Minucci Pellegrino Biagio, Cioffi Michele, Molinari Anna Maria
Abstract excerpt
INTRODUCTION: Male Breast Cancer (MBC) is a rare disease, about 1% of all breast cancers worldwide and less than 1% of cancers occurring in men. The bilateral male breast cancer (bMBC) is extremely rare. Germline mutations of BRCA1/BRCA2 genes are associated with a significantly increased risk of cancer in MBC; the role of PALB2 remains to be clarified. Our main goal was to provide contribution on...
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