Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results.

Breast cancer research and treatment - 1 Feb 2017

Pritzlaff Mary, Summerour Pia, McFarland Rachel, Li Shuwei, Reineke Patrick, Dolinsky Jill S, Goldgar David E, Shimelis Hermela, Couch Fergus J, Chao Elizabeth C, LaDuca Holly

Abstract excerpt

PURPOSE: Genetic predisposition to male breast cancer (MBC) is not well understood. The aim of this study was to better define the predisposition genes contributing to MBC and the utility of germline multi-gene panel testing (MGPT) for explaining the etiology of MBCs. METHODS: Clinical histories and molecular results were retrospectively reviewed for 715 MBC patients who underwent MGPT from March 2012 to June...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms, Male
Share to Checkpoint Kinase 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fanconi Anemia Complementation Group N Protein

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Genetic Testing

Share to Germ-Line Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 28008555
DOI: 10.1007/s10549-016-4085-4
PMCID: PMC5241330

Genes

BRCA2
CHEK2
BRCA1
PALB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results.PMID 28008555Read ↗

Insight into genetic susceptibility to male breast cancer by multigene panel testing: Results from a multicenter study in ItalySemantic proximity Read ↗

Male Breast Cancer: From Molecular Genetics to Clinical ManagementSemantic proximity Read ↗

Male Breast Cancer in the Age of Genetic Testing: An Opportunity for Early Detection, Tailored Therapy, and Surveillance.Semantic proximity Read ↗

Multigene assessment of genetic risk for women for two or more breast cancers.Semantic proximity Read ↗

Male breast cancer risk associated with pathogenic variants in genes other than BRCA1/2: an Italian case-control study.Semantic proximity Read ↗

Pathogenic variants among females with breast cancer and a non-breast cancer reveal opportunities for cancer interception.Semantic proximity Read ↗

Hereditary breast cancer syndromes and genetic testingSemantic proximity Read ↗

Pathogenic variant detection rate varies considerably in male breast cancer families and sporadic cases: minimal additional contribution beyond BRCA2, BRCA1 and CHEK2.Semantic proximity Read ↗

Multigene panel testing results in patients with multiple breast cancer primaries.Semantic proximity Read ↗

Associations Between Cancer Predisposition Testing Panel Genes and Breast Cancer.Semantic proximity Read ↗

Genetic risk assessment and prevention: the role of genetic testing panels in breast cancer.Semantic proximity Read ↗

Genetic Predisposition to Male Breast Cancer: A Case Series.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.