Article
Synergistic effect of sclerostin and angiotensin II receptor 1 polymorphism on arterial stiffening.
Biomarkers in medicine - 1 Feb 2020
Mayer Otto, Seidlerová Jitka, Kučera Radek, Kučerová Alena, Černá Václava, Gelžinský Július, Mateřánková Markéta, Mareš Štěpán, Kordíková Veronika, Pešta Martin, Topolčan Ondřej, Cífková Renata, Filipovský Jan
Abstract excerpt
Aim: We aimed to establish the association between sclerostin (a glycoprotein involved in bone metabolism) and development of pulse wave velocity (PWV) in the general population. Methods: A prospective cohort study with a total of 522 subjects. Aortic PWV was measured twice (at baseline and after approximately 8 years of follow-up) and intraindividual change in PWV per year (ΔPWV/year) was calculated. Results:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.