The role of genotype/phenotype at apurinic/apyrimidinic endonuclease Rs1130409 in renal cell carcinoma.

doi:10.4103/CJP.CJP_72_19

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Article

The role of genotype/phenotype at apurinic/apyrimidinic endonuclease Rs1130409 in renal cell carcinoma.

The Chinese journal of physiology - 1 Jan 2000

Liao Cheng-Hsi, Chang Wen-Shin, Liao Jiuan-Miaw, Wu Hsi-Chin, Shen Te-Chun, Yang Jai-Sing, Tsai Fuu-Jen, Tsai Chia-Wen, Yu Chien-Chih, Bau Da-Tian

Abstract excerpt

The DNA repair capacity plays a critical role in maintaining the genomic stability and gatekeeping for individual cancer risk. In this study, we aim at evaluation the role of the Asp148Glu (rs1130409) variant at apurinic/apyrimidinic endonuclease (APE) gene in renal cell carcinoma (RCC) risk and the contribution of different genotypes to its transcriptional mRNA levels. In the case-control study, 92 RCC patients...

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PMID: 32056986
DOI: 10.4103/CJP.CJP_72_19

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