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Article

Meta-analysis and systematic review of ADGRL3 (LPHN3) polymorphisms in ADHD susceptibility.

Molecular psychiatry - 1 Jun 2021

Bruxel E M, Moreira-Maia C R, Akutagava-Martins G C, Quinn T P, Klein M, Franke B, Ribasés M, Rovira P, Sánchez-Mora C, Kappel D B, Mota N R, Grevet E H, Bau C H D, Arcos-Burgos M, Rohde L A, Hutz M H

Abstract excerpt

The gene encoding adhesion G protein-coupled receptor L3 (ADGRL3, also referred to as latrophilin 3 or LPHN3) has been associated with ADHD susceptibility in independent ADHD samples. We conducted a systematic review and a comprehensive meta-analysis to summarize the associations between the most studied ADGRL3 polymorphisms (rs6551665, rs1947274, rs1947275, and rs2345039) and both childhood and adulthood ADHD....

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Share to Attention Deficit Disorder with Hyperactivity
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Share to Genetic Association Studies
Share to Genetic Predisposition to Disease
Share to Polymorphism, Single Nucleotide
Share to Receptors, G-Protein-Coupled
Share to Receptors, Peptide

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PMID: 32051549
DOI: 10.1038/s41380-020-0673-0

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