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Article

LPHN3 and attention-deficit/hyperactivity disorder: a susceptibility and pharmacogenetic study.

Genes, brain, and behavior - 1 Jun 2015

Bruxel E M, Salatino-Oliveira A, Akutagava-Martins G C, Tovo-Rodrigues L, Genro J P, Zeni C P, Polanczyk G V, Chazan R, Schmitz M, Arcos-Burgos M, Rohde L A, Hutz M H

Abstract excerpt

Latrophilin 3 (LPHN3) is a brain-specific member of the G-protein coupled receptor family associated to both attention-deficit/hyperactivity disorder (ADHD) genetic susceptibility and methylphenidate (MPH) pharmacogenetics. Interactions of LPHN3 variants with variants harbored in the 11q chromosome improve the prediction of ADHD development and medication response. The aim of this study was to evaluate the role...

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Share to Attention Deficit Disorder with Hyperactivity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Central Nervous System Stimulants

Share to Chromosomes, Human, Pair 11

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Share to Receptors, G-Protein-Coupled

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Source

Identifiers

PMID: 25989180
DOI: 10.1111/gbb.12224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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