Article
Odontogenic myxomas lack PDGFRB mutations reported in myofibromas.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Mar 2020
de Siqueira Elisa Carvalho, de Sousa Silvia Ferreira, Carlos Roman, de Andrade Bruno Augusto Benevenuto, Romañach Mário José, Gomez Ricardo Santiago, Gomes Carolina Cavaliéri
Abstract excerpt
BACKGROUND: The molecular pathogenesis of odontogenic myxoma has not been established yet. Considering that odontogenic myxoma may show myofibroblastic differentiation and myxoid areas can be observed in intra-osseous myofibromas, we tested the hypothesis whether both tumors share a common molecular profile. As recent studies have reported PDGFRB recurrent driver mutations in myofibroma, we evaluated PDGFRB...
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