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Article

Impaired Innate Immunity Mechanisms in the Brain of Alzheimer's Disease.

International journal of molecular sciences - 8 Feb 2020

Romagnoli Martina, Porcellini Elisa, Carbone Ilaria, Veerhuis Robert, Licastro Federico

Abstract excerpt

Among environmental factors likely associated with Alzheimer's disease (AD), persistent virus infections, and age-related progressive decline of immune competence might play a pivotal role. However, AD antimicrobial brain immune responses are poorly investigated. The present study focused on genes involved in antimicrobial defenses, especially against virus infections, in the AD brain. In particular, mRNA levels...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32046242
DOI: 10.3390/ijms21031126
PMCID: PMC7038145

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