Article
A novel technique for retrospective genetic analysis of the response to vaccination or infection using cell-free DNA from archived sheep serum and plasma.
Veterinary research - 5 Feb 2020
Hanks Eve, Todd Helen, Palarea-Albaladejo Javier, McNeilly Tom N, Britton Collette, Ballingall Keith T
Abstract excerpt
Genetic variation is associated with differences in disease resistance and susceptibility among individuals within a population. To date, molecular genetic analyses of host responses have relied on extraction of genomic DNA from whole blood or tissue samples. However, such samples are not routinely collected during large-scale field studies. We demonstrate that cell-free genomic DNA (cfDNA) may be extracted and...
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