Article
g you The direct determination of haplotypes from extended regions of genomic DNA.
BMC genomics - 6 Apr 2010
Stirling David, Stear Michael J
Abstract excerpt
BACKGROUND: One of the major obstacles to the exploitation of genetic variation in human medicine, veterinary medicine, and animal breeding is the difficulty in defining haplotypes in unrelated individuals. RESULTS: We have developed a Multiplex Double Amplification Refractory Mutation System combined with Solid Phase PCR on Fluorescently labelled beads. The process is inherently amenable to automation. It...
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