Article
Canine DNA subjected to whole genome amplification is suitable for a wide range of molecular applications.
The Journal of heredity - 1 Jan 2005
Short A D, Kennedy L J, Forman O, Barnes A, Fretwell N, Wiggall R, Thomson W, Ollier W E R
Abstract excerpt
Molecular and genetic studies of canine disease phenotypes can be limited by the amount of DNA available for analysis. New methods have been developed to amplify the genomic DNA of a species producing large quantities of DNA from small starting amounts. Whole genome amplification (WGA) of DNA is now being used in human studies, although this technique has not been applied extensively in veterinary research. We...
Topics
- Animals
- Cheek
- Chromatography, High Pressure Liquid
- DNA
- DNA Primers
- Dogs
- Genome
- Nucleic Acid Amplification Techniques
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide
- Reproducibility of Results
- Sequence Analysis, DNA
