Article
Restrictive cardiac phenotype as primary cause of impaired aerobic capacity in Afro-Caribbean patients with val122ile variant transthyretin amyloid cardiomyopathy.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Sept 2020
Monfort Astrid, Banydeen Rishika, Demoniere Fabrice, Courty Baptiste, Codiat Rebecca, Neviere Remi, Inamo Jocelyn
Abstract excerpt
Background: Impaired aerobic capacity in cardiac amyloidosis patients may be related to limited inotropic myocardial reserve and heart rate (HR) response limiting cardiac output rise. This study sought to investigate whether chronotropic incompetence (CI) and blunted HR recovery would be prevalent in patients with mutant transthyretin (ATTRv) cardiomyopathy.Methods and results: Eighteen ATTRv (Val122Ile) patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.