Article
Genetic polymorphisms in glutathione S-transferase T1 affect the surgical outcome of varicocelectomies in infertile patients.
Asian journal of andrology - 1 May 2009
Ichioka Kentaro, Nagahama Kanji, Okubo Kazutoshi, Soda Takeshi, Ogawa Osamu, Nishiyama Hiroyuki
Abstract excerpt
Glutathione S-transferases (GSTs), superoxide dismutase 2 (SOD2) and NAD(P)H:quinone oxidoreductase 1 (NQO1) are anti-oxidant enzyme genes. Polymorphisms of GSTs, SOD2 and NQO1 have been reported to influence individual susceptibility to various diseases. In an earlier study, we obtained preliminary findings that a subset of glutathione S-transferase T1 (GSTT1)-wt patients with varicocele may exhibit good...
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