Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Precision medicine for ovarian clear cell carcinoma based on gene alterations.

International journal of clinical oncology - 1 Mar 2020

Kuroda Takafumi, Kohno Takashi

Abstract excerpt

Ovarian clear cell carcinoma (OCCC) is a histological subtype of epithelial ovarian carcinoma prevalent in Asians. No clear therapeutic selection based on molecular profile has been implemented for this disease. Oncogenic PIK3CA mutation, which activates the PIK3CA/AKT/mTOR signaling pathway, is a promising druggable alteration in OCCC. Recent studies by our group and others have identified the ARID1A mutation as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma, Clear Cell
Share to Antimetabolites, Antineoplastic
Share to Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Deoxycytidine

Share to Enhancer of Zeste Homolog 2 Protein

Share to Gemcitabine

Share to Glutathione

Share to Molecular Targeted Therapy

Source

Identifiers

PMID: 32020380
DOI: 10.1007/s10147-020-01622-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Precision medicine for ovarian clear cell carcinoma based on gene alterations.PMID 32020380Read ↗

Treatment Strategies for ARID1A-Deficient Ovarian Clear Cell CarcinomaSemantic proximity Read ↗

Translational genomics of ovarian clear cell carcinoma.Semantic proximity Read ↗

Current Position of the Molecular Therapeutic Targets for Ovarian Clear Cell Carcinoma: A Literature ReviewSemantic proximity Read ↗

Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing.Semantic proximity Read ↗

Genomic Sub-Classification of Ovarian Clear Cell Carcinoma Revealed by Distinct Mutational SignaturesSemantic proximity Read ↗

Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma.Semantic proximity Read ↗

Targeting DNA Damage Response Pathway in Ovarian Clear Cell CarcinomaSemantic proximity Read ↗

Genomic profiling of ovarian clear cell carcinoma in Chinese patients reveals potential prognostic biomarkers for survival.Semantic proximity Read ↗

Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.Semantic proximity Read ↗

Molecular profiling reveals novel therapeutic targets and clonal evolution in ovarian clear cell carcinoma.Semantic proximity Read ↗

Molecular portraits of clear cell ovarian and endometrial carcinoma with comparison to clear cell renal cell carcinoma.Semantic proximity Read ↗

Review the progression of ovarian clear cell carcinoma from the perspective of genomics and epigenomicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.