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Beta-lactams and Beta-lactamase-inhibitors in current- or potential-clinical practice: A comprehensive update

20 Mar 2009

Abstract excerpt

The use of successive generations of beta-lactams has selected successive generations of beta-lactamases including CTX-M ESBLs, AmpC beta-lactamases, and KPC carbapenamases in Enterobacteriaceae. Moreover, this cephalosporin resistance, along with rising resistance to fluoroquinolones, is now driving the use of carbapenems and unfortunately the carbapenem resistance has emerged markedly, especially in...

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PMID: 19514910
DOI: 10.1080/10408410902733979

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