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Extended-spectrum beta-lactamases: definition, history, an update on their genetic environment and detection methods

24 Jun 2025

Abstract excerpt

Bacterial resistance remains a major challenge in the therapeutic field. Beta-lactam antibiotics are widely used to treat Enterobacteriaceae, especially third-generation cephalosporins (3GCs), which are used in infections caused by bacteria resistant to first- and second-line antibiotics. However, these bacteria have been able to develop resistance against the used antibiotics through the production of...

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PMID: 40554694
DOI: 10.1099/jmm.0.002033

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