Association study of genetic polymorphisms in proteins involved in oseltamivir transport, metabolism, and interactions with adverse reactions in Mexican patients with acute respiratory diseases.

doi:10.1038/s41397-020-0151-8

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association study of genetic polymorphisms in proteins involved in oseltamivir transport, metabolism, and interactions with adverse reactions in Mexican patients with acute respiratory diseases.

The pharmacogenomics journal - 1 Aug 2020

Bermúdez de León Mario, León-Cachón Rafael B R, Silva-Ramírez Beatriz, González-Ríos Rosa Nelly, Escobedo-Guajardo Brenda, Leyva-Parra Roberto, Tovar-Cisneros Benjamín, González-González Everardo, Alvarado-Díaz Abdiel, Vázquez-Monsiváis Ofelia, Mata-Tijerina Viviana, Puente-Lugo Lorena, Álvarez-Galván Erick, Currás-Tuala María José, Aguado-Barrera Miguel, Castorena-Torres Fabiola, Alcocer-González Juan Manuel, Elizondo Guillermo, Salinas-Martínez Ana María

Abstract excerpt

Oseltamivir, a pro-drug, is the best option for treatment and chemoprophylaxis for influenza outbreaks. However, many patients treated with oseltamivir developed adverse reactions, including hypersensitivity, gastritis, and neurological symptoms. The aim of this study was to determine the adverse drug reactions (ADRs) in Mexican patients treated with oseltamivir and whether these ADRs are associated with SNPs of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Interactions

Share to Drug-Related Side Effects and Adverse Reactions

Share to Influenza A Virus, H1N1 Subtype

Share to Influenza, Human

Share to Mexico

Share to Oseltamivir

Share to Respiration Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 32015454
DOI: 10.1038/s41397-020-0151-8
PMCID: PMC7223759

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association study of genetic polymorphisms in proteins involved in oseltamivir transport, metabolism, and interactions with adverse reactions in Mexican patients with acute respiratory diseases.PMID 32015454Read ↗

Pharmacogenetic markers and macrolide safety in influenza patients: insights from a prospective study.Semantic proximity Read ↗

Severe Delayed Drug Reactions: Role of Genetics and Viral Infections.Semantic proximity Read ↗

ABCB1 polymorphisms and neuropsychiatric adverse events in oseltamivir-treated children during influenza H1N1/09 pandemia.Semantic proximity Read ↗

Next Generation Sequencing-Based Mitochondrial Genome Analysis In Relation To The Drug- Induced Toxicity In Korean SubjectsSemantic proximity Read ↗

Harvesting Candidate Genes Responsible for Serious Adverse Drug Reactions from a Chemical-Protein InteractomeSemantic proximity Read ↗

Pharmacogenomics testing for type B adverse drug reactions to anti-infective drugs: the example of hypersensitivity to abacavir.Semantic proximity Read ↗

Pharmacogenomic Profile and Adverse Drug Reactions in a Prospective Therapeutic Cohort of Chagas Disease Patients Treated with Benznidazole.Semantic proximity Read ↗

Role of the ABCB1 Drug Transporter Polymorphisms in the Pharmacokinetics of Oseltamivir in Humans: a Preliminary Report.Semantic proximity Read ↗

Genome-Wide Association Study in Immunocompetent Patients with Delayed Hypersensitivity to Sulfonamide Antimicrobials.Semantic proximity Read ↗

Utility of some International Classification of Diseases 10th revision codes for detecting serious and interesting adverse drug reactions.Semantic proximity Read ↗

Oseltamivir-resistant pandemic (H1N1) 2009 virus infection in England and Scotland, 2009-2010.Semantic proximity Read ↗

Clinical and pharmacogenetic features of patients with upper gastrointestinal lesions at a multidisciplinary hospital: the role of nonsteroidal anti-inflammatory drugs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.