Article
ABCB1 polymorphisms and neuropsychiatric adverse events in oseltamivir-treated children during influenza H1N1/09 pandemia.
Pharmacogenomics - 1 Oct 2011
L'Huillier Arnaud G, Ing Lorenzini Kuntheavy, Crisinel Pierre-Alex, Rebsamen Michela C, Fluss Joel, Korff Christian M, Barbe Remy P, Siegrist Claire-Anne, Dayer Pierre, Posfay-Barbe Klara M, Desmeules Jules A
Abstract excerpt
AIMS: To examine the safety profile of oseltamivir in children and evaluate the impact of P-glycoprotein polymorphisms on the incidence of neuropsychiatric adverse events (NPAE) in oseltamivir-treated children. SUBJECTS & METHODS: This prospective cohort study was conducted in our tertiary care pediatric hospital (University Hospitals of Geneva, Switzerland) during the H1N1 pandemia, between 1 October 2009 and 31...
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