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Article

Severe Delayed Drug Reactions: Role of Genetics and Viral Infections.

Immunology and allergy clinics of North America - 1 Nov 2017

Pavlos Rebecca, White Katie D, Wanjalla Celestine, Mallal Simon A, Phillips Elizabeth J

Abstract excerpt

Adverse drug reactions (ADRs) are a significant source of patient morbidity and mortality and represent a major burden to health care systems and drug development. Up to 50% of such reactions are preventable. Although many ADRs can be predicted based on the on-target pharmacologic activity, ADRs arising from drug interactions with off-target receptors are recognized. Off-target ADRs include the immune-mediated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28965641
DOI: 10.1016/j.iac.2017.07.007
PMCID: PMC5702581

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