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Article

TINCR is not a non‐coding RNA but encodes a protein component of cornified epidermal keratinocytes

3 Feb 2020

Abstract excerpt

Long non-coding RNAs have been implicated in the regulation of a plethora of biological processes, yet it has been challenging to verify that they are truly not coding for proteins. Terminal differentiation-induced non-coding RNA (TINCR) is a 3.7-kilobase mRNA that is highly abundant in epidermal keratinocytes prior to cornification. Here, we report the presence of an evolutionarily conserved open reading frame...

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PMID: 32012357
DOI: 10.1111/exd.14083

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