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Article

Knockout of glial channel ACD-1 exacerbates sensory deficits in a C. elegans mutant by regulating calcium levels of sensory neurons.

Journal of neurophysiology - 1 Jan 2012

Wang Ying, D'Urso Giulia, Bianchi Laura

Abstract excerpt

Degenerin/epithelial Na(+) channels (DEG/ENaCs) are voltage-independent Na(+) or Na(+)/Ca(2+) channels expressed in many tissues and are needed for a wide range of physiological functions, including sensory perception and transepithelial Na(+) transport. In the nervous system, DEG/ENaCs are expressed in both neurons and glia. However, the role of glial vs. neuronal DEG/ENaCs remains unclear. We recently reported...

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Source

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Identifiers

PMID: 21994266
DOI: 10.1152/jn.00299.2011
PMCID: PMC3349695

Genes

ACD
TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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