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Article

Influence of MUC5B gene on antisynthetase syndrome.

Scientific reports - 29 Jan 2020

López-Mejías Raquel, Remuzgo-Martínez Sara, Genre Fernanda, Pulito-Cueto Verónica, Rozas Sonia M Fernández, Llorca Javier, Fernández David Iturbe, Cuesta Víctor M Mora, Ortego-Centeno Norberto, Gómez Nair Pérez, Mera-Varela Antonio, Martínez-Barrio Julia, López-Longo Francisco Javier, Mijares Verónica, Lera-Gómez Leticia, Usetti María Piedad, Laporta Rosalía, Pérez Virginia, Gafas Alicia De Pablo, González María Aránzazu Alfranca, Calvo-Alén Jaime, Romero-Bueno Fredeswinda, Sanchez-Pernaute Olga, Nuno Laura, Bonilla Gema, Balsa Alejandro, Hernández-González Fernanda, Grafia Ignacio, Prieto-González Sergio, Narvaez Javier, Trallero-Araguas Ernesto, Selva-O'Callaghan Albert, Gualillo Oreste, Castañeda Santos, Cavagna Lorenzo, Cifrian José M, González-Gay Miguel A

Abstract excerpt

MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity pneumonitis (CHP). Due to this, we evaluated the implication of MUC5B rs35705950 in antisynthetase syndrome (ASSD), a pathology characterised by a high ILD incidence. 160 patients with ASSD (142 with...

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Identifiers

PMID: 31996780
DOI: 10.1038/s41598-020-58400-0
PMCID: PMC6989632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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