Article
Role of MUC1 rs4072037 polymorphism and serum KL-6 levels in patients with antisynthetase syndrome.
Scientific reports - 19 Nov 2021
Remuzgo-Martínez Sara, Atienza-Mateo Belén, Ocejo-Vinyals J Gonzalo, Genre Fernanda, Pulito-Cueto Verónica, Mora-Cuesta Víctor M, Iturbe-Fernández David, Lera-Gómez Leticia, Pérez-Fernández Raquel, Prieto-Peña Diana, Irure Juan, Romero-Bueno Fredeswinda, Sanchez-Pernaute Olga, Alonso-Moralejo Rodrigo, Nuño Laura, Bonilla Gema, Vicente-Rabaneda Esther F, Grafia Ignacio, Prieto-González Sergio, Narvaez Javier, Trallero-Araguas Ernesto, Selva-O'Callaghan Albert, Gualillo Oreste, Cavagna Lorenzo, Cifrián José M, Renzoni Elisabetta A, Castañeda Santos, López-Mejías Raquel, González-Gay Miguel A
Abstract excerpt
Mucin 1/Krebs von den Lungen-6 (KL-6) is proposed as a serum biomarker of several interstitial lung diseases (ILDs), including connective tissue disorders associated with ILD. However, it has not been studied in a large cohort of Caucasian antisynthetase syndrome (ASSD) patients. Consequently, we assessed the role of MUC1 rs4072037 and serum KL-6 levels as a potential biomarker of ASSD susceptibility and for the...
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