Article
Changes in Plasma Amyloid and Tau in a Longitudinal Study of Normal Aging, Mild Cognitive Impairment, and Alzheimer's Disease.
Dementia and geriatric cognitive disorders - 1 Jan 2019
Chen Ting-Bin, Lai Yu-Hua, Ke Ting-Ling, Chen Jun-Peng, Lee Yi-Jung, Lin Szu-Ying, Lin Po-Chen, Wang Pei-Ning, Cheng Irene H
Abstract excerpt
BACKGROUND: Changes in cerebrospinal fluid, neuroimaging, and cognitive functions have been used as diagnostic biomarkers of Alzheimer's disease (AD). This study aimed to investigate the temporal trajectories of plasma biomarkers in subjects with mild cognitive impairment (MCI) and patients with AD relative to healthy controls (HCs). METHODS: In this longitudinal study, 82 participants (31 HCs, 33 MCI patients,...
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