Article
Optic cup morphogenesis requires neural crest-mediated basement membrane assembly.
Development (Cambridge, England) - 21 Feb 2020
Bryan Chase D, Casey Macaulie A, Pfeiffer Rebecca L, Jones Bryan W, Kwan Kristen M
Abstract excerpt
Organogenesis requires precise interactions between a developing tissue and its environment. In vertebrates, the developing eye is surrounded by a complex extracellular matrix as well as multiple mesenchymal cell populations. Disruptions to either the matrix or periocular mesenchyme can cause defects in early eye development, yet in many cases the underlying mechanism is unknown. Here, using multidimensional...
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