Article
Mutations in genes connected with the TCF7L2 transcription factor are associated with a poor prognosis in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Mar 2020
Rice Shawn J, Liu Xin, Hyland Victoria, Liu Zhenqiu, Belani Chandra P
Abstract excerpt
OBJECTIVES: Precision medicine with molecular profiling has revolutionized the management of lung cancer leading to improved outcomes. Patients with actionable mutations receive targeted therapy. As next-generation sequencing (NGS) becomes standard in lung cancer clinics, we sought to use molecular information to identify novel pathways to target in order to improve survival for non-small cell lung cancer (NSCLC)...
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