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Article

Increased prevalence of levofloxacin-resistant Mycobacterium tuberculosis in China is associated with specific mutations within the gyrA gene.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Mar 2020

Huo Fengmin, Zhang Fuzhen, Xue Yi, Shang Yuanyuan, Liang Qian, Ma Yifeng, Li Yunxu, Zhao Liping, Pang Yu

Abstract excerpt

OBJECTIVES: To compare the prevalence of levofloxacin (LFX) resistance and the population structure of Mycobacterium tuberculosis (MTB) with different mutations conferring LFX resistance between 2005 and 2015. METHODS: A total 542 MTB isolates were randomly selected from pulmonary tuberculosis (TB) patients in 2005 and 2015 and analyzed regarding minimum inhibitory concentrations (MICs) and quinolone...

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Identifiers

PMID: 31978580
DOI: 10.1016/j.ijid.2020.01.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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