Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Furvina inhibits the 3-oxo-C12-HSL-based quorum sensing system of Pseudomonas aeruginosa and QS-dependent phenotypes.

Biofouling - 1 Feb 2017

Borges Anabela, Sousa Pedro, Gaspar Alexandra, Vilar Santiago, Borges Fernanda, Simões Manuel

Abstract excerpt

Disruption of cell-cell communication or quorum sensing (QS) is considered a stimulating approach for reducing bacterial pathogenicity and resistance. Although several QS inhibitors (QSIs) have been discovered so far their clinical use remains distant. This problem can be circumvented by searching for QSI among drugs already approved for the treatment of different diseases. In this context, antibiotics have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 4-Butyrolactone
Share to Furans
Share to Homoserine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microbial Sensitivity Tests

Share to Molecular Docking Simulation

Share to Pseudomonas aeruginosa

Share to Quorum Sensing

Share to Virulence Factors

Source

Identifiers

PMID: 28140677
DOI: 10.1080/08927014.2017.1280732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Furvina inhibits the 3-oxo-C12-HSL-based quorum sensing system of Pseudomonas aeruginosa and QS-dependent phenotypes.PMID 28140677Read ↗

Furanone quorum-sensing inhibitors with potential as novel therapeutics against Pseudomonas aeruginosaSemantic proximity Read ↗

Quorum sensing inhibitors: a patent review (2014–2018)Semantic proximity Read ↗

Assessing the Molecular Targets and Mode of Action of Furanone C-30 on Pseudomonas aeruginosa Quorum SensingSemantic proximity Read ↗

In silico identification of quorum sensing inhibitors against LasR protein in a clinical isolate of multidrug resistant Pseudomonas aeruginosa DMC-27bSemantic proximity Read ↗

Strategies for quorum sensing inhibition as a tool for controlling Pseudomonas aeruginosa infectionsSemantic proximity Read ↗

Targeting quorum sensing mechanism: An alternative anti-virulent strategy for the treatment of bacterial infectionsSemantic proximity Read ↗

Natural Quorum Sensing Inhibitors – Small Molecules, Big MessagesSemantic proximity Read ↗

Two cinnamic acid derivatives as inhibitors of Pseudomonas aeruginosa las and pqs quorum-sensing systems: Impact on biofilm formation and virulence factorsSemantic proximity Read ↗

Novel approaches for the design and discovery of quorum-sensing inhibitorsSemantic proximity Read ↗

Quorum sensing pathways in Gram-positive and -negative bacteria: potential of their interruption in abating drug resistanceSemantic proximity Read ↗

Pleotropic potential of quorum sensing mediated N-acyl homoserine lactones (AHLs) at the LasR and RhlR receptors of Pseudomonas aeruginosaSemantic proximity Read ↗

Isoeugenol suppresses multiple quorum sensing regulated phenotypes and biofilm formation of Pseudomonas aeruginosa PAO1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.