Association between rs4149056 variant in SLCO1B1 and early discontinuation of statin after acute myocardial infarction.

doi:10.2217/pgs-2019-0109

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Article

Association between rs4149056 variant in SLCO1B1 and early discontinuation of statin after acute myocardial infarction.

Pharmacogenomics - 1 Feb 2020

Al-Salameh Abdallah, Danchin Nicolas, Verstuyft Céline, Kotti Salma, Puymirat Etienne, Ferrières Jean, Schiele François, Coste Pierre, Lemesle Gilles, Cayla Guillaume, Becquemont Laurent, Simon Tabassome

Abstract excerpt

Data from two French surveys were used to analyze the association between in-hospital statin discontinuation and SLCO1B1 polymorphism (rs4149056) in patients with acute myocardial infarction. Using TaqMan allelic discrimination assay, 1674 and 1708 patients were genotyped for SLCO1B1 in 2005 and 2010, respectively. The association with in-hospital statin discontinuation was assessed after adjusting for...

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PMID: 31967516
DOI: 10.2217/pgs-2019-0109

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