Article
SLA-1 Genetic Diversity in Pigs: Extensive Analysis of Copy Number Variation, Heterozygosity, Expression, and Breed Specificity.
Scientific reports - 20 Jan 2020
Le Minh Thong, Choi Hojun, Lee Hyejeong, Le Van Chanh Quy, Ahn Byeongyong, Ho Chak-Sum, Hong Kwonho, Song Hyuk, Kim Jin-Hoi, Park Chankyu
Abstract excerpt
Swine leukocyte antigens play indispensable roles in immune responses by recognizing a large number of foreign antigens and thus, their genetic diversity plays a critical role in their functions. In this study, we developed a new high-resolution typing method for pig SLA-1 and successfully typed 307 individuals from diverse genetic backgrounds including 11 pure breeds, 1 cross bred, and 12 cell lines. We...
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