Article
Molecular characterization of swine leukocyte antigen gene diversity in purebred Pietrain pigs.
Animal genetics - 1 Apr 2013
Essler Sabine E, Ertl Werner, Deutsch Julia, Ruetgen Barbara C, Groiss Sandra, Stadler Maria, Wysoudil Bhuma, Gerner Wilhelm, Ho Chak-Sum, Saalmueller Armin
Abstract excerpt
The porcine major histocompatibility complex (MHC) harbors the highly polymorphic swine leukocyte antigen (SLA) class I and II gene clusters encoding glycoproteins that present antigenic peptides to T cells in the adaptive immune response. In Austria, the majority of commercial pigs are F 2 descendants of F 1 Large White/Landrace hybrids paired with Pietrain boars. Therefore, the repertoire of SLA alleles and...
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