Article
MicroRNA Tough Decoy Knockdowns miR-195 and Represses Hypertrophy in Chondrocytes.
Applied biochemistry and biotechnology - 1 Jul 2020
Abbasi Pashaki Pejman, Rahim Fakher, Habibi Roudkenar Mehryar, Razavi-Toosi Smt, Ebrahimi Ammar
Abstract excerpt
Cartilage hypertrophy is a condition in which the cells are completely differentiated, and new morphological changes and mineralization prevent proper cellular functions. The occurrence of hypertrophy during differentiation fails current regenerative strategies for treatment. Strategies to minimize hypertrophy in chondrocytes are categorized into two levels of protein and gene. Among these strategies, one way to...
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