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Article

Immunological microenvironment in the testis

29 Aug 2019

Abstract excerpt

BACKGROUND: The testis is specific in that it produces haploid germ cells of which autoantigens newly appear long after the neonatal immune tolerance. Under normal condition, these autoantigens are protected by the blood-testis barrier formed by Sertoli cells. Thus, the testis is an immunologically privileged site where haploid cells are protected from autoimmune attack. METHODS: The immunological...

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PMID: 31956282
DOI: 10.1002/rmb2.12293

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