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Unwrapping the immunological alterations in testicular germ cell tumors: From immune homeostasis to malignancy and emerging immunotherapies

10 Sept 2024

Abstract excerpt

BACKGROUND: Testicular germ cell tumors (TGCTs), derived from primordial germ cells, are rare malignancies with high curative potential. However, the emergence of new evidence indicating that 15% of patients experience tumor progression, leading to death, underscores the need for innovative therapeutics. OBJECTIVES: This review aimed to explore the immune status in maintaining testicular health and the...

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PMID: 39253799
DOI: 10.1111/andr.13751

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