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Article

Immunology and immunopathology of the male genital tract: Control and impairment of immune privilege in the testis and in semen

1 Sept 2001

Abstract excerpt

It has long been known that the testis is an immunologically privileged site in the body, and that human seminal plasma possesses a generalized immunosuppressive activity. Multiple factors participate in the establishment of immunotolerance in the testis: the blood-tubular barrier; the local production of immunosuppressive molecules by Sertoli cells; and the Fas system as regulator of immunological homeostasis in...

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PMID: 11556490
DOI: 10.1093/humupd/7.5.444

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