Article
Stepwise evolution and convergent recombination underlie the global dissemination of carbapenemase-producing Escherichia coli.
Genome medicine - 20 Jan 2020
Patiño-Navarrete Rafael, Rosinski-Chupin Isabelle, Cabanel Nicolas, Gauthier Lauraine, Takissian Julie, Madec Jean-Yves, Hamze Monzer, Bonnin Remy A, Naas Thierry, Glaser Philippe
Abstract excerpt
BACKGROUND: Carbapenem-resistant Enterobacteriaceae are considered by WHO as "critical" priority pathogens for which novel antibiotics are urgently needed. The dissemination of carbapenemase-producing Escherichia coli (CP-Ec) in the community is a major public health concern. However, the global molecular epidemiology of CP-Ec isolates remains largely unknown as well as factors contributing to the acquisition of...
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