Article
MUCIN-4 (MUC4) is a novel tumor antigen in pancreatic cancer immunotherapy.
Seminars in immunology - 1 Feb 2020
Gautam Shailendra K, Kumar Sushil, Dam Vi, Ghersi Dario, Jain Maneesh, Batra Surinder K
Abstract excerpt
Pancreatic cancer (PC) is a highly lethal malignancy with a dismal five-year survival rate. This is due to its asymptomatic nature, lack of reliable biomarkers, poor resectability, early metastasis, and high recurrence rate. Limited efficacies of current treatment modalities treatment-associated toxicity underscore the need for the development of immunotherapy-based approaches. For non-resectable, locally...
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