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Article

Elevated Amygdala Activity in Young Adults With Familial Risk for Depression: A Potential Marker of Low Resilience.

Biological psychiatry. Cognitive neuroscience and neuroimaging - 1 Feb 2020

Barbour Tracy, Holmes Avram J, Farabaugh Amy H, DeCross Stephanie N, Coombs Garth, Boeke Emily A, Wolthusen Rick P F, Nyer Maren, Pedrelli Paola, Fava Maurizio, Holt Daphne J

Abstract excerpt

BACKGROUND: Amygdala overactivity has been frequently observed in patients with depression, as well as in nondepressed relatives of patients with depression. A remaining unanswered question is whether elevated amygdala activity in those with familial risk for depression is related to the presence of subthreshold symptoms or to a trait-level vulnerability for illness. METHODS: To examine this question, functional...

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Identifiers

PMID: 31948836
DOI: 10.1016/j.bpsc.2019.10.010
PMCID: PMC7448615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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