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Article

Amygdala-function perturbations in healthy mid-adolescents with familial liability for depression.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 May 2014

Pilhatsch Maximilian, Vetter Nora C, Hübner Thomas, Ripke Stephan, Müller Kathrin U, Marxen Michael, Rodehacke Sarah, Mennigen Eva, Schmidt Dirk, Kroemer Nils B, Smolka Michael N

Abstract excerpt

OBJECTIVE: Functional magnetic resonance imaging (fMRI) studies have identified increased amygdala responses to negative stimuli as a risk marker of depression in adults, and as a state marker of depression in adults and adolescents. Hyperreactivity of the amygdala has been linked to negatively biased emotional processing in depression. However, no study has elucidated whether similar amygdala perturbations can...

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Identifiers

PMID: 24745955
DOI: 10.1016/j.jaac.2014.02.010

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