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Article

A Polymorphism in the Catalase Gene Promoter Confers Protection against Severe RSV Bronchiolitis.

Viruses - 3 Jan 2020

Chambliss Jeffrey M, Ansar Maria, Kelley John P, Spratt Heidi, Garofalo Roberto P, Casola Antonella

Abstract excerpt

Respiratory syncytial virus (RSV) infection is associated with oxidative lung injury, decreased levels of antioxidant enzymes (AOEs), and the degradation of the transcription factor NF-E2-related factor 2 (NRF2), a master regulator of AOE expression. Single nucleotide polymorphisms (SNPs) in AOE and NRF2 genes have been associated with various lung disorders. To test whether specific NRF2 and/or AOE gene SNPs in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31947722
DOI: 10.3390/v12010057
PMCID: PMC7019864

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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