Article
Genetic characterization of influenza A(H3N2) viruses circulating in coastal Kenya, 2009-2017.
Influenza and other respiratory viruses - 1 May 2020
Owuor D Collins, Ngoi Joyce M, Otieno James R, Otieno Grieven P, Nyasimi Festus M, Nyiro Joyce U, Agoti Charles N, Chaves Sandra S, Nokes D James
Abstract excerpt
BACKGROUND: Influenza viruses evolve rapidly and undergo immune driven selection, especially in the hemagglutinin (HA) protein. We report amino acid changes affecting antigenic epitopes and receptor-binding sites of A(H3N2) viruses circulating in Kilifi, Kenya, from 2009 to 2017. METHODS: Next-generation sequencing (NGS) was used to generate A(H3N2) virus genomic data from influenza-positive specimens collected...
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