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Article

Emergence of a novel subclade of influenza A(H3N2) virus in London, December 2016 to January 2017.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 23 Feb 2017

Harvala Heli, Frampton Dan, Grant Paul, Raffle Jade, Ferns Ruth Bridget, Kozlakidis Zisis, Kellam Paul, Pillay Deenan, Hayward Andrew, Nastouli Eleni

Abstract excerpt

We report the molecular investigations of a large influenza A(H3N2) outbreak, in a season characterised by sharp increase in influenza admissions since December 2016. Analysis of haemagglutinin (HA) sequences demonstrated co-circulation of multiple clades (3C.3a, 3C.2a and 3C.2a1). Most variants fell into a novel subclade (proposed as 3C.2a2); they possessed four unique amino acid substitutions in the HA protein...

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Identifiers

PMID: 28251889
DOI: 10.2807/1560-7917.ES.2017.22.8.30466
PMCID: PMC5356434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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