Article
Molecular Evolutionary Dynamics of Respiratory Syncytial Virus Group A in Recurrent Epidemics in Coastal Kenya.
Journal of virology - 15 May 2016
Otieno James R, Agoti Charles N, Gitahi Caroline W, Bett Ann, Ngama Mwanajuma, Medley Graham F, Cane Patricia A, Nokes D James
Abstract excerpt
UNLABELLED: The characteristic recurrent epidemics of human respiratory syncytial virus (RSV) within communities may result from the genetic variability of the virus and associated evolutionary adaptation, reducing the efficiency of preexisting immune responses. We analyzed the molecular evolutionary changes in the attachment (G) glycoprotein of RSV-A viruses collected over 13 epidemic seasons (2000 to 2012) in...
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