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Article

Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts.

Journal of medical genetics - 1 Feb 2012

Goodarzi Mark O, Jones Michelle R, Li Xiaohui, Chua Angela K, Garcia Obed A, Chen Yii-Der I, Krauss Ronald M, Rotter Jerome I, Ankener Wendy, Legro Richard S, Azziz Ricardo, Strauss Jerome F, Dunaif Andrea, Urbanek Margrit

Abstract excerpt

BACKGROUND: Polycystic ovary syndrome (PCOS) is a complex endocrine disorder with a strong familial component. PCOS is characterised by hyperandrogenaemia and irregular menses. A recent genome-wide association study (GWAS) of PCOS in a Chinese cohort identified three reproducible PCOS susceptibility loci mapping to 2p16.3 (luteinising hormone/choriogonadotropin receptor; LHCGR), 2p21 (thyroid associated protein;...

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Identifiers

PMID: 22180642
DOI: 10.1136/jmedgenet-2011-100427
PMCID: PMC3536488

Genes

LHCGR
MADD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts.PMID 22180642Read ↗

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Replication study and meta-analysis of selected genetic variants and polycystic ovary syndrome susceptibility in Asian population.Semantic proximity Read ↗

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