Article
[Growth Hormone-Insulin Growth Factor I (GH-IGF-I) axis and growth].
Annales d'endocrinologie - 1 Oct 2013
Castell A-L, Sadoul J-L, Bouvattier C
Abstract excerpt
Normal human linear growth results from an evolutionary process expressing the sum effect of multiple genes. The growth hormone (GH) - insulin like growth factor (IGF)-I axis is one of the main actors in the growth process. Defects in this axis can be responsible for short or tall stature. Short stature is defined as smaller than - 2 standard deviations (SD). It is a very common reason for consultation in...
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