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Article

A mosquito salivary protein promotes flavivirus transmission by activation of autophagy

14 Jan 2020

Abstract excerpt

Abstract Transmission from an infected mosquito to a host is an essential process in the life cycle of mosquito-borne flaviviruses. Numerous studies have demonstrated that mosquito saliva facilitates viral transmission. Here we find that a saliva-specific protein, named Aedes aegypti venom allergen-1 ( Aa VA-1), promotes dengue and Zika virus transmission by activating autophagy in host immune cells of the...

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PMID: 31937766
DOI: 10.1038/s41467-019-14115-z

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