Article
Association of the Polymorphism rs13259960 in SLEAR With Predisposition to Systemic Lupus Erythematosus.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Jun 2020
Fan Zhen, Chen Xiaowei, Liu Lu, Zhu Caihong, Xu Jinhua, Yin Xianyong, Sheng Yujun, Zhu Zhengwei, Wen Leilei, Zuo Xianbo, Zheng Xiaodong, Zhang Yaohua, Xu Jingkai, Huang He, Zhou Fusheng, Sun Liangdan, Luo Jianjun, Zhang Dongdong, Chen Xiaomin, Cui Ya, Hao Yajing, Cui Yong, Zhang Xuejun, Chen Runsheng
Abstract excerpt
OBJECTIVE: Genome-wide association studies have identified many susceptibility loci for systemic lupus erythematosus (SLE). However, most of these loci are located in noncoding regions of the genome. Long noncoding RNAs (lncRNAs) are pervasively expressed and have been reported to be involved in various diseases. This study aimed to explore the genetic significance of lncRNAs in SLE. METHODS: A genome-wide survey...
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