Article
Use of serum KL-6 level for detecting patients with restrictive allograft syndrome after lung transplantation.
PloS one - 1 Jan 2020
Berastegui Cristina, Gómez-Ollés Susana, Mendoza-Valderrey Alberto, Pereira-Veiga Thais, Culebras Mario, Monforte Victor, Saez Berta, López-Meseguer Manuel, Sintes-Permanyer Helena, Ruiz de Miguel Victoria, Bravo Carlos, Sacanell Judit, Ramon María-Antonia, Romero Laura, Deu María, Román Antonio
Abstract excerpt
KL-6 is an antigen produced mainly by damaged type II pneumocytes that is involved in interstitial lung disease. Chronic lung allograft dysfunction (CLAD) after lung transplantation (LT) is a major concern for LT clinicians, especially in patients with restrictive allograft syndrome (RAS). We investigated KL-6 levels in serum and bronchoalveolar lavage fluid (BALF) as a potential biomarker of the RAS phenotype....
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